1. Chemical Identity INN: Norethisterone Acetate USAN: Norethindrone Acetate Chemical Name: 17α-Ethynyl-17β-acetoxy-estr-4-en-3-one Molecular Formula: C₂₂H₂₈O₃ Molecular Weight: 340.46 g/mol Chemical Class: Synthetic progestogen (progestin); sex hormone CAS Number: 51-98-9 Norethisterone acetate is the acetate ester of norethisterone, developed to improve stability and pharmacokinetic behavior while retaining potent progesterone-like activity. 2. Structural Characteristics This compound is based on the 19-nor-estrane steroid nucleus and features: 17α-ethynyl group (confers oral activity) 17β-acetate ester (prodrug functionality) 3-keto group critical for progestational action Δ4 double bond (C4-C5) Absence of the C19 methyl group The acetate ester is readily hydrolyzed in vivo to active norethisterone. 3. Physicochemical Properties Appearance: White or almost white crystalline powder Odor: Practically odorless Solubility: Practically insoluble in water Soluble in ethanol, methanol, chloroform, acetone Melting Point: ~196-198 °C Lipophilicity: Moderate (enhanced vs. parent alcohol) Stability: Stable under dry, cool, light-protected conditions 4. Mechanism of Action Norethisterone acetate acts as a prodrug: Ester hydrolysis releases norethisterone Norethisterone binds to progesterone receptors (PR) Modulates gene transcription leading to: Transformation of proliferative to secretory endometrium Suppression of ovulation via inhibition of LH/FSH Increased cervical mucus viscosity Reduced endometrial receptivity At therapeutic doses, estrogenic effects are negligible; mild androgenic activity may occur. About the Company GST Registration Date: 2023 Legal Status of Firm: Limited Company Number of Employees: "},{"DATA":"2023","TITLE":"Year of Establishment"},{"DATA":"","TITLE":"Standards \u0026 Quality Certifications"},{"DATA":"Limited Company (Ltd./Pvt.Ltd.)","TITLE":"Legal Status of Firm"},{"DATA":"","TITLE":""},{"DATA":"","TITLE":"Annual Turnover"},{"DATA":"","TITLE":"GST Partner Name"},{"DATA":"2023","TITLE":"GST Registration Year"},{"DATA":"Limited Company","TITLE":"GST Legal Status of Firm"},{"DATA":"Trader - Wholesaler/Distributor","TITLE":"GST Nature of Business"},{"DATA":"1.5 - 5 Cr","TITLE":"GST Annual Turnover"},{"DATA":"Office / Sale Office,Import,Export,Retail Business,Wholesale Business,Others","TITLE":"GST Additional NOB"}],"CAT_ID":"187","CITY":"Vadodara","CITY_ID":"70491","COMPANYNAME":"Suktas Organic And Lifescience Private Limited","COMPANY_VIDEO_LINK":"","CTA_DOC_PATH":"","DELIVERY_TIME":"3 weeks","DISCLAIMER_KEY":1,"DISCLAIMER_TEXT":["Verification of drug license 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